| Cat. No. |
Product Name |
Information |
| PC-20845 |
EMD386088 hydrochloride
5-HT6 agonist
|
EMD386088 hydrochloride is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20844 |
EMD386088
5-HT6 agonist
|
EMD386088 is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20843 |
SAM-531
5-HT6 agonist
|
SAM-531 (Cerlapirdine, WAY-262531) is a selective, highly potent, 5-HT6 receptor antagonist. |
| PC-38596 |
SB 224289 hydrochloride
5-HT1B antagonist
|
SB 224289 hydrochloride is a potent, selective 5-HT1B inverse agonist/antagonist with pKi value of 8.16, displays >75-fold selectivity over all other 5-HT receptors. |
| PC-73302 |
AVN-492
5-HT6 antagonist
|
AVN-492 is a highly potent and selective 5-HT6 receptor antagonist with Ki of 91 pM, >1000-fold selectivity over 5-HT2BR (Ki=170 nM). |
| PC-73301 |
ST1936 oxalate
5-HT6 agonist
|
ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors. |
| PC-73300 |
LP-211
5-HT7 agonist
|
LP-211 is a potent, selective, and BBB-penetrant 5-HT7 receptor agonist with Ki of 0.58 nM, high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). |
| PC-73299 |
Usmarapride
5-HT4 agonist
|
Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist with EC50of 44 nM. |
| PC-45693 |
Lumateperone tosylate
|
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
| PC-45233 |
Iloperidone hydrochloride
|
An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors. |
| PC-42792 |
Risperidone mesylate
|
An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties. |
| PC-42791 |
Risperidone hydrochloride
|
An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties. |
