S32212 | 5-HT2C antagonist | Probechem Biochemicals

Chemical Structure : S32212

S32212 (S 32212)

Catalog No.: PC-22310Not For Human Use, Lab Use Only.

S32212 is a combined serotonin (5-HT)(2C) receptor inverse agonist and α(2)-adrenoceptor antagonist with pKi of8.2 (h5-HT2C), pKi of 7.2-8.2 for α(2A), α(2B) and α(2C).

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Biological Activity

S32212 is a combined serotonin (5-HT)(2C) receptor inverse agonist and α(2)-adrenoceptor antagonist with pKi of8.2 (h5-HT2C), pKi of 7.2-8.2 for α(2A), α(2B) and α(2C).

Physicochemical Properties

M.Wt	452.98
Formula	C25H29ClN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,2-Dihydro-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3H-benz[e]indole-3-carboxamide hydrochloride

References

1. Millan MJ, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):750-64.

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S32212 (S 32212)

Biological Activity

Physicochemical Properties

References

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