Catalog No.: PC-22773Not For Human Use, Lab Use Only.
8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells).
8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). 8-OH-DPAT reduces hippocampal 5-HT levels following systemic administration in rats in vivo.
Physicochemical Properties
M.Wt
247.38
Formula
C16H25NO
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
8-hydroxy-2-(di-n-propylamino)tetralin
References
1. Hamon M, et al. Eur J Pharmacol. 1984 May 4;100(3-4):263-76.
