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Chemical Structure : 8-OH-DPAT
CAS No.: 78950-78-4
Catalog No.: PC-22773Not For Human Use, Lab Use Only.
8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells).
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|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
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8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells).
8-OH-DPAT reduces hippocampal 5-HT levels following systemic administration in rats in vivo.
| M.Wt | 247.38 | |
| Formula | C16H25NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
8-hydroxy-2-(di-n-propylamino)tetralin |
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1. Hamon M, et al. Eur J Pharmacol. 1984 May 4;100(3-4):263-76.
2. Ahlenius S, et al. Eur J Pharmacol. 1984 Apr 6;99(4):279-86.
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