8-OH-DPAT | 5-HT1A agonist | Probechem Biochemicals

Chemical Structure : 8-OH-DPAT

CAS No.: 78950-78-4

8-OH-DPAT (8-Hydroxy-DPAT)

Catalog No.: PC-22773Not For Human Use, Lab Use Only.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$128	In stock
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Biological Activity

8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells).
8-OH-DPAT reduces hippocampal 5-HT levels following systemic administration in rats in vivo.

Physicochemical Properties

M.Wt	247.38
Formula	C16H25NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-hydroxy-2-(di-n-propylamino)tetralin

References

1. Hamon M, et al. Eur J Pharmacol. 1984 May 4;100(3-4):263-76.

2. Ahlenius S, et al. Eur J Pharmacol. 1984 Apr 6;99(4):279-86.

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8-OH-DPAT (8-Hydroxy-DPAT)

Biological Activity

Physicochemical Properties

References

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