| Cat. No. |
Product Name |
Information |
| PC-21668 |
PZ-1444
5-HT6R inverse agonist
|
PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM. |
| PC-21667 |
PZ-1922
5-HT6 antagonist
|
PZ-1922 is a potent, triple-acting 5-HT6R/5-HT3R antagonist and MAO-B reversible inhibitor with Ki of 17/0.45 nM (5-HT6R/5-HT3R), and pIC50 of 8.93 for MAO-B. |
| PC-21666 |
5-HT6 receptor antagonist 15
5-HT6 antagonist
|
5-HT6 receptor antagonist 15 is a first-in-class, selenium containing, highly potent and selective 5-HT6R antagonist with Ki of 14 nM. |
| PC-21178 |
25B-NBOMe
5-HT2A agonist
|
25B-NBOMe is a highly selective 5-HT2A receptor agonist with Ki of 0.05 nM, 100-fold selective over 5-HT2C (Ki=4.6 nM). |
| PC-21048 |
NU-1223
5-HT2C agonist
|
NU-1223 is a β carboline analog of alstonine and serotonin 5-HT2C receptor agonist, blocks phencyclidine and amphetamine-induced hyperactivity in subchronic phencyclidine mice. |
| PC-20963 |
Pimavanserin
5-HT2A inverse agonist
|
Pimavanserin (ACP-103) is a potent, selective, orally active 5-HT2A receptor inverse agonist, competitively antagonizes the binding of [(3)H]ketanserin to heterologously expressed human 5-HT(2A) receptors with pKi of 9.3 in membranes and 9.70 in whole cells. |
| PC-20845 |
EMD386088 hydrochloride
5-HT6 agonist
|
EMD386088 hydrochloride is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20844 |
EMD386088
5-HT6 agonist
|
EMD386088 is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20843 |
SAM-531
5-HT6 agonist
|
SAM-531 (Cerlapirdine, WAY-262531) is a selective, highly potent, 5-HT6 receptor antagonist. |
| PC-49806 |
5-HT2A agonist (R)-70
|
5-HT2A agonist (R)-70 is a potent selective 5-HT2A receptor partial agonist with EC50 of 110 nM in calcium flux assays, and Ki value of 880 nM. |
| PC-49805 |
5-HT2A agonist (R)-69
|
5-HT2A agonist (R)-69 is a potent selective 5-HT2A receptor partial agonist with EC50 of 41 nM in calcium flux assays, and Ki value of 680 nM. |
| PC-49160 |
ASP5736
5-HT5A antagonist
|
AS5736 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 3.6, 1.7 and 4.4 nM against human, rat, mouse 5-HT5A receptors, respectively. |
