| Cat. No. |
Product Name |
Information |
| PC-63485 |
SB-258585
5-HT6 antagonist
|
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes. |
| PC-63484 |
SB-399885 hydrochloride
5-HT6 antagonist
|
SB-399885 hydrochloride is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors. |
| PC-63483 |
SB-399885
5-HT6 antagonist
|
SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors. |
| PC-63427 |
JNJ-5234801
|
JNJ-5234801 is an atypical anxiolytic targeting 5-HT2 receptor, has demonstrated oral activity in animal models of anxiety.. |
| PC-63401 |
JNJ-18038683 free base
5-HT7 antagonist
|
JNJ-18038683 free base is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays. |
| PC-63400 |
JNJ-18038683
5-HT7 antagonist
|
JNJ-18038683 is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays. |
| PC-63289 |
CYD-1-79
5-HT2C PAM
|
CYD-1-79 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM), potentiates 5-HT-evoked intracellular calcium release in cells stably expressing the human 5-HT2CR but not the 5-HT2AR cells. |
| PC-63256 |
DSP-1053
SERT inhibitor, 5-HT1A agonist
|
DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively. |
| PC-43401 |
BRL54443
5-HT1E/1F agonist
|
BRL54443 is a potent, releative selective 5-HT1E/1F agonist with Ki of 2/1 nM, respectively. |
| PC-43384 |
BRL-15572 dihydrochloride
5-HT1D antagonist
|
BRL-15572 dihydrochloride is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B. |
| PC-43382 |
WAY-100635 maleate
5-HT1A antagonist
|
WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-43156 |
Prucalopride succinate
5-HT4 agonist
|
Prucalopride succinate (R-108512) is a potent, selective 5-HT4 receptor agonist with pKi of 8.6 and 8.1 for 5-HT4a and 5-HT4b, >290-fold higher affinity for 5-HT4 receptors than for other receptors. |
