| Cat. No. |
Product Name |
Information |
| PC-61583 |
GSK-588045
5-HT1A/B/D antagonist
|
GSK-588045 is a potent and selective 5-HT1A/B/D receptor antagonist with Ki of 9.5/8.8/9.8, respectively. |
| PC-61522 |
SUVN-502 mesylate hydrate
|
SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-61521 |
SUVN-502 mesylate
5-HT6 antagonist
|
SUVN-502 (Masupirdine, SUVN502) mesylate is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-61511 |
AVN-211
5-HT6 antagonist
|
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM. |
| PC-61504 |
AVN-101
5-HT7 antagonist
|
AVN-101 is a higly potent, orally bioavailable, BBB permeable 5-HT7 receptor antagonist with Ki of 153 pM, with slightly lesser potency toward 5-HT6, 5-HT2A and 5HT-2C (Ki = 1.2-2.0 nM). |
| PC-61502 |
AVN-322
5-HT6 antagonist
|
AVN-322 is a highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia. |
| PC-61500 |
SUVN-502
5-HT6 antagonist
|
SUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-61221 |
MKC-733
5-HT3 agonist
|
MKC-733 (Pumosetrag, DDP 733) is a potent, selective, orally active 5-HT3 receptor agonist with high affinity for canine intestinal smooth muscle 5-HT3 receptors. |
| PC-61178 |
SB-357134
5-HT6 antagonist
|
SB-357134 is a potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5, displays 1300-fold selectivity over other 13 5-HT receptor subtypes. |
| PC-61117 |
WAY 163909
5-HT2C agonist
|
WAY 163909 is a highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485 nM, respectively). |
| PC-61106 |
MIN-117
5-HT1A/2A antagonist
|
MIN-117 (WF-516) is a small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors. |
| PC-61081 |
PF-03246799
5-HT2C agonist
|
PF-03246799 (PF-3246799) is a potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A. |
