Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-GPCR-5-HT Receptor-Eletriptan hydrobromide
Eletriptan hydrobromide

Chemical Structure : Eletriptan hydrobromide

CAS No.: 177834-92-3

Eletriptan hydrobromide (UK 116044 hydrobromide, UK116044 hydrobromide)

Catalog No.: PC-61867Not For Human Use, Lab Use Only.

Eletriptan (UK 116044) hydrobromide is a potent, selective, and orally active 5-HT1B/1D receptor agonist with Ki of 0.92 nM and 3.14 nM respectively.

Packing Price Stock Quantity
10 mg $68 In stock
25 mg $98 In stock
50 mg $158 In stock
100 mg $248 In stock
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Eletriptan (UK 116044) hydrobromide is a potent, selective, and orally active 5-HT1B/1D receptor agonist with Ki of 0.92 nM and 3.14 nM respectively.
Eletriptan (UK 116044) significantly increases occluded wedge pressure and mean pulmonary artery pressure in vivo, with no significant coronary artery constriction, and obstructive coronary artery disease.
Eletriptan (UK 116044) displays antimigraine activity.

Physicochemical Properties

M.Wt 463.43
Formula C22H26N2O2S.HBr
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide

References

1. Napier C, et al. Eur J Pharmacol. 1999 Mar 5;368(2-3):259-68.

2. Gupta P, et al. Eur J Pharmacol. 1999 Feb 19;367(2-3):283-90.

3. Muir DF, et al. Clin Pharmacol Ther. 1999 Jul;66(1):85-90.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: