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GSK-812

Chemical Structure : GSK-812

CAS No.: 630407-66-8

GSK-812 (GSK812)

Catalog No.: PC-61812Not For Human Use, Lab Use Only.

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.

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    Biological Activity

    GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.

    Physicochemical Properties

    M.Wt 471.996
    Formula C25H26ClNO4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

    References

    1. Baranov P, et al. J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422.

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