| Cat. No. |
Product Name |
Information |
| PC-45034 |
RU 24969
5-HT1B agonist
|
RU 24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors with Ki values of 2.5 and 0.38 nM respectively, with preference for 5-HT1B. |
| PC-42651 |
Nelotanserin
5-HT2A antagonist
|
Nelotanserin (RVT-102, APD125) is a potent, selective 5-HT2A inverse agonist with pKi of 9.2. |
| PC-45757 |
Eptapirone
5-HT1A agonist
|
Eptapirone (F11440) is a potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33. |
| PC-45945 |
Alosetron hydrochloride
5-HT3 antagonist
|
Alosetron (GR-68755) hydrochloride is a potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome. |
| PC-45944 |
Alosetron
5-HT3 antagonist
|
Alosetron (GR-68755) is a potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome. |
| PC-42547 |
WAY-100635
5-HT1A antagonist
|
WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-42653 |
Ketanserin
5-HT2A antagonist
|
Ketanserin (R41468) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-45229 |
Ziprasidone hydrochloride monohydrate
D2/5-HT2A antagonist
|
Ziprasidone hydrochloride monohydrate (CP-88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-43963 |
Ziprasidone
D2/5-HT2A antagonist
|
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-23513 |
LY266097 hydrochloride
5-HT2B antagonist
|
LY266097 hydrochloride is a potent, selective 5-HT2B receptor antagonist with pKi value of 9.8, >100-fold selective over 5-HT2A and 5-HT2C. |
| PC-23512 |
MRS8209
5-HT2B antagonist
|
MRS8209 is a potent, peripheral subtype-selective 5-HT2B serotonin receptor antagonist with Ki of 4.27 nM (human 5-HT2B), shows reduced affinity at the m5-HT2BR and r5-HT2BR (100-fold and 10-fold). |
| PC-23422 |
Aripiprazole
Dopamine agonist
|
Aripiprazole (OPC-14597) is an atypical antipsychotic, and potent and high-affinity dopamine D2 receptor (D2R) partial agonist, also is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. |
