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Chemical Structure : Nelotanserin
CAS No.: 839713-36-9
Catalog No.: PC-42651Not For Human Use, Lab Use Only.
A potent, selective 5-HT2A inverse agonist with pKi of 9.2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $280 | In stock | |
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | Get quote |
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A potent, selective 5-HT2A inverse agonist with pKi of 9.2; displays >30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors; prevents DOI-induced hypolocomotion and increases sleep consolidation; orally active.
Depression
Phase 2 Discontinued
| M.Wt | 437.2381 | |
| Formula | C18H15BrF2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
Urea, N-[3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-N'-(2,4-difluorophenyl)- |
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1. Teegarden BR, et al. J Med Chem. 2010 Mar 11;53(5):1923-36.
2. Al-Shamma HA, et al. J Pharmacol Exp Ther. 2010 Jan;332(1):281-90.
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