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Chemical Structure : Iloperidone
CAS No.: 133454-47-4
Catalog No.: PC-45232Not For Human Use, Lab Use Only.
Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $78 | In stock | |
| 100 mg | $128 | In stock | |
| 250 mg | $198 | In stock | |
| 1 g | Get quote |
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Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors.
Iloperidone (HP-873) is used for the treatment of schizophrenia.
| M.Wt | 426.4806 | |
| Formula | C24H27FN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]- |
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1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
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