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NAN-190 hydrobromide

Chemical Structure : NAN-190 hydrobromide

CAS No.: 115338-32-4

NAN-190 hydrobromide (NAN190 hydrobromide;NAN 190 hydrobromide)

Catalog No.: PC-45732Not For Human Use, Lab Use Only.

NAN-190 hydrobromide is a potent, selective 5-HT1A receptor antagonist with Ki of 0.6 nM.

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100 mg $188 In stock
200 mg $328 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NAN-190 hydrobromide is a potent, selective 5-HT1A receptor antagonist with Ki of 0.6 nM.
NAN-190 also potently blocks the α2-adrenergic receptor.
NAN-190 antagonizes the stimulation by norepinephrine of phosphoinositide turnover in rat cortical slices.

Physicochemical Properties

M.Wt 474.3907
Formula C23H28BrN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 36.23 mg/mL

Chemical Name/SMILES

1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrobromide (1:1)

References

1. Claustre Y, et al. Eur J Pharmacol. 1991 Oct 29;204(1):71-7.

2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.

3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.

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