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RU 24969

Chemical Structure : RU 24969

CAS No.: 66611-26-5

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RU 24969 (RU24969, RU-24969)

Catalog No.: PC-45034Not For Human Use, Lab Use Only.

RU 24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors with Ki values of 2.5 and 0.38 nM respectively, with preference for 5-HT1B.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RU 24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors with Ki values of 2.5 and 0.38 nM respectively, with preference for 5-HT1B.
RU 24969 inhibited the rate of synthesis of 5-HT in rat brain by about 50% (10mg/kg)

Physicochemical Properties

M.Wt 228.2896
Formula C14H16N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL
Chemical Name/SMILES

1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-

References

1. Green AR, et al. Neuropharmacology. 1984 Jun;23(6):655-61.

2. Harrison AA, et al. Psychopharmacology (Berl). 1999 Jan;141(3):242-50.

3. Parsons LH, et al. J Neurosci. 1998 Dec 1;18(23):10078-89.

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