| Cat. No. |
Product Name |
Information |
| PC-43963 |
Ziprasidone
D2/5-HT2A antagonist
|
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-23913 |
ST1936
5-HT6 agonist
|
ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors. |
| PC-23513 |
LY266097 hydrochloride
5-HT2B antagonist
|
LY266097 hydrochloride is a potent, selective 5-HT2B receptor antagonist with pKi value of 9.8, >100-fold selective over 5-HT2A and 5-HT2C. |
| PC-23512 |
MRS8209
5-HT2B antagonist
|
MRS8209 is a potent, peripheral subtype-selective 5-HT2B serotonin receptor antagonist with Ki of 4.27 nM (human 5-HT2B), shows reduced affinity at the m5-HT2BR and r5-HT2BR (100-fold and 10-fold). |
| PC-23422 |
Aripiprazole
Dopamine agonist
|
Aripiprazole (OPC-14597) is an atypical antipsychotic, and potent and high-affinity dopamine D2 receptor (D2R) partial agonist, also is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. |
| PC-23392 |
Flucopride
5-HT4R agonist, AChE inhibitor
|
Flucopride is a potent, dual serotonin subtype 4 receptor (5-HT4R) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 9.6 nM (5-HT4R) and IC50 of 24 nM (hAChE). |
| PC-23390 |
Donecopride
5-HT4R agonist, AChE inhibitor
|
Donecopride (MR31147) is a potent, dual serotonin subtype 4 receptor (5-HT4) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 8.5 nM (5-HT4eR) and IC50 of 16 nM (hAChE). |
| PC-23335 |
Ondansetron hydrochloride dihydrate
5-HT3 antagonist
|
Ondansetron hydrochloride dihydrate (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23334 |
Ondansetron hydrochloride
5-HT3 antagonist
|
Ondansetron hydrochloride (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23333 |
Ondansetron
5-HT3 antagonist
|
Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23306 |
Vilazodone
5-HT1A agonist, SSRI
|
Vilazodone (EMD68843, SB659746A) is a potent, dual 5-HT1A agonist and serotonin reuptake inhibitor (SSRI) with IC50 of 0.2 nM at the human 5-HT1A receptor and 0.5 nM for the SERT. |
| PC-23281 |
RS67333 hydrochloride
5-HT4 agonist
|
RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. |
