| Cat. No. |
Product Name |
Information |
| PC-23392 |
Flucopride
5-HT4R agonist, AChE inhibitor
|
Flucopride is a potent, dual serotonin subtype 4 receptor (5-HT4R) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 9.6 nM (5-HT4R) and IC50 of 24 nM (hAChE). |
| PC-23390 |
Donecopride
5-HT4R agonist, AChE inhibitor
|
Donecopride (MR31147) is a potent, dual serotonin subtype 4 receptor (5-HT4) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 8.5 nM (5-HT4eR) and IC50 of 16 nM (hAChE). |
| PC-23335 |
Ondansetron hydrochloride dihydrate
5-HT3 antagonist
|
Ondansetron hydrochloride dihydrate (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23334 |
Ondansetron hydrochloride
5-HT3 antagonist
|
Ondansetron hydrochloride (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23333 |
Ondansetron
5-HT3 antagonist
|
Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23306 |
Vilazodone
5-HT1A agonist, SSRI
|
Vilazodone (EMD68843, SB659746A) is a potent, dual 5-HT1A agonist and serotonin reuptake inhibitor (SSRI) with IC50 of 0.2 nM at the human 5-HT1A receptor and 0.5 nM for the SERT. |
| PC-23281 |
RS67333 hydrochloride
5-HT4 agonist
|
RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. |
| PC-23280 |
Prucalopride
5-HT4 agonist
|
Prucalopride (R-108512) is a potent, selective 5-HT4 receptor agonist with pKi of 8.6 and 8.1 for 5-HT4a and 5-HT4b, >290-fold higher affinity for 5-HT4 receptors than for other receptors. |
| PC-23244 |
GSK215083
5-HT6 antagonist
|
GSK215083 is a potent, selective 5-HT6 receptor antagonist. |
| PC-22773 |
8-OH-DPAT
5-HT1A agonist
|
8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.19, has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). |
| PC-22599 |
MT-1207 hydrochloride
α1/5-HT2A antagonist
|
MT-1027 hydrochloride is a highly potent α1 adrenoceptor and 5-HT2A receptor antagonist with IC50 of <0.1 nM and 0.27 nM respectively. |
| PC-22598 |
MT-1207
α1/5-HT2A antagonist
|
MT-1027 is a highly potent α1 adrenoceptor and 5-HT2A receptor antagonist with IC50 of <0.1 nM and 0.27 nM respectively. |
