| Cat. No. |
Product Name |
Information |
| PC-45945 |
Alosetron hydrochloride
5-HT3 antagonist
|
Alosetron (GR-68755) hydrochloride is a potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome. |
| PC-45944 |
Alosetron
5-HT3 antagonist
|
Alosetron (GR-68755) is a potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome. |
| PC-42547 |
WAY-100635
5-HT1A antagonist
|
WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-42654 |
Ketanserin tartrate
5-HT2A antagonist
|
Ketanserin tartrate (R41468 tartrate) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-42653 |
Ketanserin
5-HT2A antagonist
|
Ketanserin (R41468) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-45229 |
Ziprasidone hydrochloride monohydrate
D2/5-HT2A antagonist
|
Ziprasidone hydrochloride monohydrate (CP-88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-43963 |
Ziprasidone
D2/5-HT2A antagonist
|
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-25075 |
(S)-Hydroxy Iloperidone
CAS 501373-88-2
|
(S)-Hydroxy Iloperidone (Milsaperidone) is a metabolite of Iloperidone, which is an atypical antipsychotic, binds to adrenergic α1 and α2c receptors with pKi of 9.2 and 7.7 respectively. |
| PC-25028 |
Remlifanserin
5-HT2A inverse agonist
|
Remlifanserin is a potent, selective 5-HT2A serotonin receptor inverse agonist. |
| PC-25012 |
WAY-208466
5-HT6 agonist
|
WAY-208466 (WAY 208466 dihydrochloride) is a potent and selective 5-HT6 receptor agonist with EC50 of 7.3 nM for human 5-HT6 receptor, shows antidepressant-like and anxiolytic-like effects. |
| PC-24958 |
AVN-101 hydrochloride
5-HT7 antagonist
|
Maritupirdine hydrochloride (AVN-101) is a higly potent, orally bioavailable, BBB permeable 5-HT7 receptor antagonist with Ki of 153 pM, with slightly lesser potency toward 5-HT6, 5-HT2A and 5HT-2C (Ki = 1.2-2.0 nM). |
| PC-24893 |
MDL11939
5-HT2A antagonist
|
MDL11939 (Glemanserin) is a potent and selective antagonist for serotonin receptor 5-HT2A with Ki values of 2.89, 0.54 and 2.5 nM for rat, rabbit and human 5-HT2A receptors, respectively. |
