| Cat. No. |
Product Name |
Information |
| PC-73300 |
LP-211
5-HT7 agonist
|
LP-211 is a potent, selective, and BBB-penetrant 5-HT7 receptor agonist with Ki of 0.58 nM, high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). |
| PC-73299 |
Usmarapride
5-HT4 agonist
|
Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist with EC50of 44 nM. |
| PC-43516 |
SB 242084 hydrochloride
|
SB 242084 is a potent, selective, brain penetrant 5-HT2C receptor antagonist with pKi of 9.0, 100- and 158-fold selectivity over the closely related 5-HT2B and 5-HT2A subtypes. |
| PC-35019 |
Ro 60-0175 fumarate
|
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively. |
| PC-63484 |
SB-399885 hydrochloride
|
SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors. |
| PC-43384 |
BRL-15572 dihydrochloride
|
BRL-15572 is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B. |
| PC-43156 |
Prucalopride succinate
|
Prucalopride succinate (R-108512) is a potent, selective 5-HT4 receptor agonist with pKi of 8.6 and 8.1 for 5-HT4a and 5-HT4b, >290-fold higher affinity for 5-HT4 receptors than for other receptors. |
| PC-63186 |
DSP-6952 hydrobromide
|
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
| PC-62095 |
Velusetrag hydrochloride
|
Velusetrag (TD-5108) is a potent, selective and oral 5-HT4 receptor agonist with pKi of 7.7, shows >500-fold selectivity over other 5-HT receptors. |
| PC-61868 |
Eletriptan
|
Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist. |
| PC-61503 |
AVN-322 free base
|
A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia. |
| PC-61080 |
PF-04781340
|
A potent, selective, CNS penetrant 5-HT2C receptor agonist with Ki of 3 nM and EC50 of 9 nM, without significant P-gp efflux liability. |
