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Alosetron

Chemical Structure : Alosetron

CAS No.: 122852-42-0

Alosetron (GR-68755X;GR-68755)

Catalog No.: PC-45944Not For Human Use, Lab Use Only.

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.

Irritable Bowel Syndrome

Approved

Physicochemical Properties

M.Wt 294.351
Formula C17H18N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-

References

1. Audolfsson G, et al. Aliment Pharmacol Ther. 1999 May;13 Suppl 2:39-47.

2. Zhai J, et al. J Pharmacol Exp Ther. 1999 Oct;291(1):374-82.

3. Saslow SB, et al. Gut. 1998 May;42(5):628-34.

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