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Alosetron hydrochloride

Chemical Structure : Alosetron hydrochloride

CAS No.: 122852-69-1

Alosetron hydrochloride (GR-68755X;GR-68755)

Catalog No.: PC-45945Not For Human Use, Lab Use Only.

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.

Irritable Bowel Syndrome

Approved

Physicochemical Properties

M.Wt 330.812
Formula C17H19ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1)

References

1. Audolfsson G, et al. Aliment Pharmacol Ther. 1999 May;13 Suppl 2:39-47.

2. Zhai J, et al. J Pharmacol Exp Ther. 1999 Oct;291(1):374-82.

3. Saslow SB, et al. Gut. 1998 May;42(5):628-34.

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