Chemical Structure : Ziprasidone
CAS No.: 146939-27-7
Catalog No.: PC-43963Not For Human Use, Lab Use Only.
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively.
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Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively.
Ziprasidone also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
Ziprasidone exhibits potent antipsychotic activity in vivo.
M.Wt | 412.9356 | |
Formula | C21H21ClN4OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro- |
1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
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