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Chemical Structure : WAY-100635
CAS No.: 162760-96-5
Catalog No.: PC-42547Not For Human Use, Lab Use Only.
WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
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|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $108 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | $458 | In stock | |
| 250 mg | Get quote |
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WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
WAY-100635 completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.
| M.Wt | 422.563 | |
| Formula | C25H34N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide |
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1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
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