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RS67333 hydrochloride

Chemical Structure : RS67333 hydrochloride

CAS No.: 168986-60-5

RS67333 hydrochloride

Catalog No.: PC-23281Not For Human Use, Lab Use Only.

RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum.
RS67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors.
RS67333 hydrochloride has neuroprotective effects.

Physicochemical Properties

M.Wt 389.36
Formula C19H30Cl2N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-Amino-5-chloro-2-methoxyphenyl)-3-(1-butylpiperidin-4-yl)propan-1-one hydrochloride

References

1. R M Eglen, et al. 1995 Aug;115(8):1387-92.

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