Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Perlapine
Catalog No.: PC-62934Not For Human Use, Lab Use Only.
Perlapine (AW-14233.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Perlapine (AW-14233;HF-2333;Hypnodine) is a potent antihistamine that has high affinity for dopamine D1, α1, α2 and 5-HT2A receptors with IC50 of 198, 19, 4945 and 70 nM, respectively; also has anticholinergic, antiserotonergic, antiadrenergic and antidopaminergic activity; also is a highly potent hM3Dq agonist (EC50=2.8 nM) but do not activate the native human M3 receptor (hM3, EC50>30 uM).
| M.Wt | 291.398 | |
| Formula | C19H21N3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Stille G, et al. Psychopharmacologia. 1973 Feb 20;28(4):325-37.
2. Wilk S, et al. Eur J Pharmacol. 1977 Jan 7;41(1):65-72.
3. Chen X, et al. ACS Chem Neurosci. 2015 Mar 18;6(3):476-84.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
