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Chemical Structure : Naronapride
Catalog No.: PC-62096Not For Human Use, Lab Use Only.
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
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Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
Naronapride (ATI-7505) displays negligible affinity for Kv11.1 channels (Ki=24,500 nM), and no effect on cardiac repolarization.
Naronapride (ATI-7505) shows potential for treatment of gastrointestinal motility disorders.
| M.Wt | 537.098 | |
| Formula | C27H41ClN4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Manabe N, et al. Expert Opin Investig Drugs. 2010 Jun;19(6):765-75.
2. Bowersox SS, et al. Drug Metab Dispos. 2011 Jul;39(7):1170-80.
3. Hoffman JM, et al. Gastroenterology. 2012 Apr;142(4):844-854.e4.
4. Camilleri M, et al. Neurogastroenterol Motil. 2007 Jan;19(1):30-8.
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