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Chemical Structure : DSP-6952 hydrobromide
Catalog No.: PC-63186Not For Human Use, Lab Use Only.
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c.
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DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c; enhances gastric motility and causes colonic giant migrating contractions (GMCs) associated with defecation in conscious dogs, having ED50 value for inducing GMCs of 1.56 mg/kg; rapidly increases fecal wet weight without increasing fluid content in mice (1-10 mg/kg, p.o.).
| M.Wt | 535.864 | |
| Formula | C21H32BrClN4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mine Y, et al. Eur J Pharmacol. 2018 Feb 9;826:123-132.
2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105.
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