BRL-15572 dihydrochloride | 5-HT1D antagonist

Chemical Structure : BRL-15572 dihydrochloride

CAS No.: 193611-72-2

BRL-15572 dihydrochloride (BRL15572, BRL 15572)

Catalog No.: PC-43384Not For Human Use, Lab Use Only.

BRL-15572 dihydrochloride is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B.

Packing	Price	Stock
10 mg	$58	In stock
25 mg	$98	In stock
50 mg	$158	In stock
100 mg	$258	In stock
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

BRL-15572 dihydrochloride is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B.
BRL-15572 dihydrochloride shows binding affinities for 5-HT1A, 5-HT1B, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT6 and 5-HT7 with pKi of 7.7, 6.1, 5.2, 6.0, 6.6, 7.4, 6.2, 5.9 and 6.3, respectively.

Physicochemical Properties

M.Wt	479.8696
Formula	C25H29Cl3N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Piperazineethanol, 4-(3-chlorophenyl)-.alpha.-(diphenylmethyl)-, hydrochloride (1:2)

References

1. Price GW, et al. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20.

2. Schlicker E, et al. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):321-7.

3. De Vries P, et al. Eur J Pharmacol. 1998 Nov 27;362(1):69-72.

4. Marcoli M, et al. Br J Pharmacol. 1999 Feb;126(3):607-12.

BRL-15572 dihydrochloride (BRL15572, BRL 15572)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.