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Chemical Structure : BRL-15572 dihydrochloride
Catalog No.: PC-43384Not For Human Use, Lab Use Only.
BRL-15572 is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B.
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BRL-15572 is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B; shows binding affinities for 5-HT1A, 5-HT1B, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT6 and 5-HT7 with pKi of 7.7, 6.1, 5.2, 6.0, 6.6, 7.4, 6.2, 5.9 and 6.3, respectively.
| M.Wt | 479.8696 | |
| Formula | C25H29Cl3N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Price GW, et al. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20.
2. Schlicker E, et al. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):321-7.
3. De Vries P, et al. Eur J Pharmacol. 1998 Nov 27;362(1):69-72.
4. Marcoli M, et al. Br J Pharmacol. 1999 Feb;126(3):607-12.
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