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WAY-100635 maleate

Chemical Structure : WAY-100635 maleate

CAS No.: 1092679-51-0

WAY-100635 maleate (WAY100635 maleate)

Catalog No.: PC-43382Not For Human Use, Lab Use Only.

WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
WAY-100635 completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.

Physicochemical Properties

M.Wt 538.64
Formula C29H38N4O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

N-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide Maleate

References

1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.

2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.

3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.

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