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Chemical Structure : AGH-192
Catalog No.: PC-73304Not For Human Use, Lab Use Only.
AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.
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AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM.
AGH-192 displays excellent water solubility, high selectivity over related CNS targets, high metabolic stability, oral bioavailability and low cytotoxicity.
AGH-192 could crosses blood-brain barrier to a high extent.
AGH-192 alleviates the symptoms of neuropathic pain in a mouse model.
| M.Wt | 355.155 | |
| Formula | C13H11FIN3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Adam S Hogendorf, et al. Eur J Med Chem. 2019 May 15;170:261-275.
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