AGH-107 | 5-HT7 agonist | Probechem Biochemicals

Chemical Structure : AGH-107

AGH-107 (AGH107)

Catalog No.: PC-73303Not For Human Use, Lab Use Only.

AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.

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Biological Activity

AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.
AGH-107 exhibited high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.

Physicochemical Properties

M.Wt	337.164
Formula	C13H12IN3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(1-ethyl-1H-imidazol-5-yl)-5-iodo-1H-indole

References

1. Hogendorf AS, et al. Sci Rep. 2017 May 4;7(1):1444.

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AGH-107 (AGH107)

Biological Activity

Physicochemical Properties

References

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