Luvesilocin (RE104) | 5-HT2A agonist | Probechem Biochemicals

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Chemical Structure : RE104

RE104 (Luvesilocin, RE-104)

Catalog No.: PC-22530Not For Human Use, Lab Use Only.

Luvesilocin (RE104) is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.

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Biological Activity

Luvesilocin (RE104) is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.
A single dose of RE104 (1 mg/kg) significantly reduced mean immobility time at 1 week compared with vehicle (P < 0.001), confirming translational antidepressant potential.

Physicochemical Properties

M.Wt	374.48
Formula	C21H30N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((3-(2-(diisopropylamino)ethyl)-1H-indol-4-yl)oxy)-5-oxopentanoic acid

References

1. Bryson N, et al. ACS Chem Neurosci. 2024 May 17. doi: 10.1021/acschemneuro.4c00058.

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RE104 (Luvesilocin, RE-104)

Biological Activity

Physicochemical Properties

References

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