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RE104

Chemical Structure : RE104

CAS No.: 2756001-39-3

RE104 (RE-104)

Catalog No.: PC-22530Not For Human Use, Lab Use Only.

RE104 is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RE104 is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.
A single dose of RE104 (1 mg/kg) significantly reduced mean immobility time at 1 week compared with vehicle (P < 0.001), confirming translational antidepressant potential.

Physicochemical Properties

M.Wt 374.48
Formula C21H30N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((3-(2-(diisopropylamino)ethyl)-1H-indol-4-yl)oxy)-5-oxopentanoic acid

References

1. Bryson N, et al. ACS Chem Neurosci. 2024 May 17. doi: 10.1021/acschemneuro.4c00058.

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