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Chemical Structure : SB269970
Catalog No.: PC-22277Not For Human Use, Lab Use Only.
SB269970 (SB-269970) is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors.
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SB269970 (SB-269970) is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors.
SB-269970 (0.03-1 microM) inhibited the 5-CT concentration-response with no significant alteration in the maximal response.
| M.Wt | 352.49 | |
| Formula | C18H28N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Roberts C, et al. Br J Pharmacol. 2001 Apr;132(7):1574-80.
2. Hagan JJ, et al. Br J Pharmacol. 2000 Jun;130(3):539-48.
3. Lovell PJ, et al. J Med Chem. 2000 Feb 10;43(3):342-5.
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