Cat. No. |
Product Name |
Information |
PC-63224 |
PKC beta II inhibitor H6
|
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM, extracted from patent WO 2008096260 A1 as compound example H6.. |
PC-42969 |
Indolactam V
|
Indolactam V ((-)-Indolactam V) is an indole alkaloid tumor promoter that activates protein kinase C (PKC), binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3.4 nM and 1 uM, respectively. |
PC-62814 |
PKC-IN-7
|
PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM. |
PC-62477 |
UCN-01
|
UCN-01 (7-Hydroxystaurosporine. |
PC-62415 |
PS-432
|
PS-432 is an allosteric inhibitor of PKCι and PKCζ with IC50 of 16.9 and 18.5 uM, respectively. |
PC-62078 |
LY379196
|
LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM). |
PC-62077 |
CGP-53353
|
CGP-53353 (DAPH-7) is a selective inhibitor of PKCβII with IC50 of 0.41 uM, shows weak activity on PKCβI with IC50 of 3.8 uM. |
PC-61793 |
Rottlerin
|
Rottlerin (Mallotoxin. |
PC-61296 |
OSU-2S
|
A non-immunosuppressive FTY720 analogue, PKCδ activator with higher antiproliferative potency with IC50 of 2.4, 2.4, and 3.5 uM in Huh7, Hep3B, and PLC5 cells, respectively. |
PC-70263 |
Calphostin C
|
A potent, selective and photo-dependent inhibitor of PKC with IC50 of 50 nM. |
PC-60684 |
Go 6976
|
A potent, selective protein kinase C (PKC) inhibitor that selectively inhibits PKCα and PKCβ1 with IC50 of 2.3 and 6.2 nM, respectively. |
PC-60366 |
PKC-IN-6c
|
A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM). |