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Phorbol 12-myristate 13-acetate

Chemical Structure : Phorbol 12-myristate 13-acetate

CAS No.: 16561-29-8

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Phorbol 12-myristate 13-acetate (PMA)

Catalog No.: PC-45546Not For Human Use, Lab Use Only.

Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.
Phorbol 12-myristate 13-acetate (PMA) is a potent tumor promoter often employed in biomedical research.

Physicochemical Properties

M.Wt 616.825
Formula C36H56O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 62 mg/mL
Chemical Name/SMILES

Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester

References

1. Xu F, et al. Br J Pharmacol. 2003 Sep;140(2):413-21.

2. Blumberg PM, et al. Cancer Res. 1988 Jan 1;48(1):1-8.

3. Niedel JE, et al. Proc Natl Acad Sci U S A. 1983 Jan;80(1):36-40.

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