| Cat. No. |
Product Name |
Information |
| PC-62415 |
PS432
PKC inhibitor
|
PS432 is an allosteric inhibitor of PKCι and PKCζ with IC50 of 16.9 and 18.5 uM, respectively. |
| PC-62375 |
BJE6-106
PKCδ inhibitor
|
BJE6-106 (B106) is a potent, selective PKCδ inhibitor with IC50 of 50 nM, displays excellent selectivity over classical PKC isozymes (a 1,000-fold PKCδ selectivity over PKCα). |
| PC-62078 |
LY379196
PKCβ inhibitor
|
LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM). |
| PC-62077 |
CGP-53353
PKCβII inhibitor
|
CGP-53353 (DAPH-7) is a selective inhibitor of PKCβII with IC50 of 0.41 uM, shows weak activity on PKCβI with IC50 of 3.8 uM. |
| PC-60994 |
AS2521780
PKCθ inhibitor
|
AS2521780 is a potent, selective, orally bioavailable PKCθ inhibitor that inhibits combinant human PKCθ enzyme with IC50 of 0.48 nM, >30-fold higher than other PKC isoforms. |
| PC-60684 |
Go 6976
PKC inhibitor
|
Go 6976 is a potent, selective protein kinase C (PKC) inhibitor that selectively inhibits PKCα and PKCβ1 with IC50 of 2.3 and 6.2 nM, respectively. |
| PC-42543 |
Sotrastaurin
PKC inhibitor
|
Sotrastaurin (AEB071) is a potent, selective, orally available pan-PKC inhibitor with Ki of 0.22-3.2 nM for PKC isotypes. |
| PC-42441 |
Ruboxistaurin hydrochloride
PKCβ inhibitor
|
Ruboxistaurin hydrochloride (LY333531) is a potent, selective, ATP-competitive, orally available PKC beta (PKCβ) inhibitor with IC50 of 4.7 and 5.9 nM for PKCβ I and PKCβ II, respectively. |
| PC-42542 |
Enzastaurin
PKCβ inhibitor
|
Enzastaurin (LY317615) is a potent, selective, ATP-competitive PKCβ inhibitor with IC50 of 6 nM. |
| PC-42473 |
PKC412
PKC inhibitor
|
Midostaurin (CGP-41231, PKC-412) is a potent, selective PKC inhibitor with IC50 of 50 nM. |
| PC-45546 |
Phorbol 12-myristate 13-acetate
PKC activator
|
Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. |
| PC-21981 |
CIDD-0072424
PKC epsilon inhibitor
|
CIDD-0072424 is a potent, selective inhibitor of protein kinase C epsilon (PKCε, PKC epsilon) with IC50 of 54 nM, high selectivity over other PKC isoforms. |
