Catalog No.: PC-63489Not For Human Use, Lab Use Only.
PKCiota-IN-49 (PKCiota inhibitor 49) is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.8 nM, >20-fold selectivity over PKC-α (IC50=71 nM) and PKC-β (IC50=350 nM).
PKCiota-IN-49 (PKCiota inhibitor 49) is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.8 nM, >20-fold selectivity over PKC-α (IC50=71 nM) and PKC-β (IC50=350 nM).
PKCiota-IN-49 inhibits PKC-ι on the phosphorylation of substrate ECT2 in HCCLM3 cells with IC50 of 3.0 uM.
