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Chemical Structure : PKC-IN-7
Catalog No.: PC-62814Not For Human Use, Lab Use Only.
PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.
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PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
| M.Wt | 443.931 | |
| Formula | C26H22ClN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786.
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