| Cat. No. |
Product Name |
Information |
| PC-42473 |
PKC412
PKC inhibitor
|
Midostaurin (CGP41231, PKC-412) is a potent, selective PKC inhibitor with IC50 of 50 nM, also inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 of 20-500 nM. |
| PC-45546 |
Phorbol 12-myristate 13-acetate
PKC activator
|
Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. |
| PC-25662 |
MS-553
PKCβ inhibitor
|
MS-553 is a potent, ATP competitive, reversible inhibitor of PKC isoform PKCβ, has potential to overcome BTKi mediated resistance. |
| PC-24787 |
Acteoside
PKC inhibitor
|
Acteoside (Verbascoside) is a small molecule ATP-competitive inhibitor of protein kinase C (PKC) with IC50 of 25 uM, shows antitumor, anti-inflammatory and antineuropathic pain activity. |
| PC-23471 |
Staurosporine
PKC inhibitor, Apoptosis inducer
|
Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. |
| PC-23429 |
Ruboxistaurin
PKCβ inhibitor
|
Ruboxistaurin (LY333531) is a potent, selective, ATP-competitive, orally available PKC beta (PKCβ) inhibitor with IC50 of 4.7 and 5.9 nM for PKCβ I and PKCβ II, respectively. |
| PC-23428 |
Ro 31-8220 mesylate
PKC inhibitor
|
Ro 31-8220 mesylate (Bisindolylmaleimide IX) is a potent pan-PKC inhibitor with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. |
| PC-23427 |
Ro 31-8220
PKC inhibitor
|
Ro 31-8220 (Bisindolylmaleimide IX) is a potent pan-PKC inhibitor with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. |
| PC-22772 |
PS428
PRK2 inhibitor
|
PS428 is a small molecule, allosteric inhibitor of protein kinase C-related kinase 2 (PKN2/PRK2), binds to the PIF-pocket of PRK2 and allosterically inhibits activated PRK2. |
| PC-21446 |
Go 6983
PKC inhibitor
|
Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively. |
| PC-42784 |
CGP60474
|
A potent CDK1 inhibitor with IC50 of 17 nM. |
