| Cat. No. |
Product Name |
Information |
| PC-60684 |
Go6976
PKC inhibitor
|
Go6976 is a potent, selective protein kinase C (PKC) inhibitor that selectively inhibits PKCα and PKCβ1 with IC50 of 2.3 and 6.2 nM, respectively. |
| PC-60366 |
PKC-IN-6c
PKC inhibitor
|
PKC inhibitor 6c (PKC-IN-6c) is a potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM). |
| PC-42543 |
Sotrastaurin
PKC inhibitor
|
Sotrastaurin (AEB071) is a potent, selective, orally available pan-PKC inhibitor with Ki of 0.22-3.2 nM for PKC isotypes. |
| PC-42441 |
Ruboxistaurin hydrochloride
PKCβ inhibitor
|
Ruboxistaurin hydrochloride (LY333531) is a potent, selective, ATP-competitive, orally available PKC beta (PKCβ) inhibitor with IC50 of 4.7 and 5.9 nM for PKCβ I and PKCβ II, respectively. |
| PC-42542 |
Enzastaurin
PKCβ inhibitor
|
Enzastaurin (LY317615) is a potent, selective, ATP-competitive PKCβ inhibitor with IC50 of 6 nM. |
| PC-42473 |
Midostaurin
PKC inhibitor
|
Midostaurin (CGP41231, PKC-412) is a potent, selective PKC inhibitor with IC50 of 50 nM, also inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 of 20-500 nM. |
| PC-45546 |
Phorbol 12-myristate 13-acetate
PKC activator
|
Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. |
| PC-27178 |
ICA-1S
PKC-iota inhibitor
|
ICA-1S is a specific, allosteric inhibitor of protein kinase C-iota (PKC-ι). |
| PC-27152 |
NPC-15437
PKC inhibitor
|
NPC-15437 (NPC15437) is a specific, competitive small molecule protein kinase C (PKC) inhibitor with IC50 of 19 uM. |
| PC-25662 |
MS-553
PKCβ inhibitor
|
MS-553 is a potent, ATP competitive, reversible inhibitor of PKC isoform PKCβ, has potential to overcome BTKi mediated resistance. |
| PC-23471 |
Staurosporine
PKC inhibitor, Apoptosis inducer
|
Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. |
| PC-23429 |
Ruboxistaurin
PKCβ inhibitor
|
Ruboxistaurin (LY333531) is a potent, selective, ATP-competitive, orally available PKC beta (PKCβ) inhibitor with IC50 of 4.7 and 5.9 nM for PKCβ I and PKCβ II, respectively. |
