PKC (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-23428	Ro 31-8220 mesylate PKC inhibitor	Ro 31-8220 mesylate (Bisindolylmaleimide IX) is a potent pan-PKC inhibitor with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.
PC-23427	Ro 31-8220 PKC inhibitor	Ro 31-8220 (Bisindolylmaleimide IX) is a potent pan-PKC inhibitor with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.
PC-23426	GF109203X PKC inhibitor	GF109203X (Bisindolylmaleimide I) is a potent, cell-permeable and reversible PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ respectively.
PC-22772	PS428 PRK2 inhibitor	PS428 is a small molecule, allosteric inhibitor of protein kinase C-related kinase 2 (PKN2/PRK2), binds to the PIF-pocket of PRK2 and allosterically inhibits activated PRK2.
PC-21981	CIDD-0072424 PKC epsilon inhibitor	CIDD-0072424 is a potent, selective inhibitor of protein kinase C epsilon (PKCε, PKC epsilon) with IC50 of 54 nM, high selectivity over other PKC isoforms.
PC-21446	Go 6983 PKC inhibitor	Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively.
PC-42784	CGP60474	A potent CDK1 inhibitor with IC50 of 17 nM.

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