CGP60474 |CAS:164658-13-3 Probechem Biochemicals

Chemical Structure : CGP60474

CAS No.: 164658-13-3

Catalog No.: PC-42784Not For Human Use, Lab Use Only.

A potent CDK1 inhibitor with IC50 of 17 nM.

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50 mg	$400	In stock
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Biological Activity

A potent CDK1 inhibitor with IC50 of 17 nM; exhibits lower potency at CDK2 (IC50=50-80nM) and moderate potency at CDK4 (IC50=700 nM).

M.Wt	355.8214
Formula	C18H18ClN5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-

1. Ruetz S, et al. Curr Med Chem Anticancer Agents. 2003 Jan;3(1):1-14.

2. Kuo GH, et al. J Med Chem. 2005 Jul 14;48(14):4535-46.