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Chemical Structure : Staurosporine
CAS No.: 62996-74-1
Catalog No.: PC-23471Not For Human Use, Lab Use Only.
Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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Staurosporine (STS) is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.
Staurosporine also inhibits TAOK2 with an IC50 of 3 μM.
Staurosporine is a classical apoptosis inducer.
| M.Wt | 466.54 | |
| Formula | C28H26N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(5S,6R,7R,9R)-6-Methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one |
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1. Meggio F, et al. Eur J Biochem. 1995 Nov 15;234(1):317-22.
2. Yoshizawa S, et al. Cancer Res. 1990 Aug 15;50(16):4974-8.
3. Nabeshima T, et al. J Pharmacol Exp Ther. 1991 May;257(2):562-6.
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