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Go 6983

Chemical Structure : Go 6983

CAS No.: 133053-19-7

Go 6983 (Gö 6983, Goe 6983)

Catalog No.: PC-21446Not For Human Use, Lab Use Only.

Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively.

Physicochemical Properties

M.Wt 442.52
Formula C26H26N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-(3-(Dimethylamino)propyl)-5-methoxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

References

1. Gschwendt M, et al. FEBS Lett, 1996, 392(2), 77-80.

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