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Chemical Structure : ζ-Stat
CAS No.: 3316-02-7
Catalog No.: PC-35337Not For Human Use, Lab Use Only.
ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, shows only 13% inhibition on PKC-I at 20 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
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| 100 mg | Get quote |
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ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, shows only 13% inhibition on PKC-I at 20 uM.
ζ-Stat downregulates TNF-α induced NF-κB translocation to the nucleus there by inducing apoptosis.
ζ-Stat significantly decreases melanoma cell proliferation of SK-MEL-2 and MeWo.
| M.Wt | 384.344 | |
| Formula | C10H8O10S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
8-hydroxy-1,3,6-naphthalenetrisulfonic acid |
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1. Islam SMA, et al. Biochim Biophys Acta. 2018 Apr;1865(4):650-664.
2. Ratnayake WS, et al. Cell Adh Migr. 2018 May 21:1-17.
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