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Cat. No. Product Name Information
PC-20721

PF-4693627

mPGES-1 inhibitor

PF-4693627 is a potent, selective and orally bioavailable mPGES-1 inhibitor with IC50 of 3 nM.
PC-20720

UT-11

mPGES-1 inhibitor

UT-11 is a potent microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, inhibits PGE2 production from human SK-N-AS and murine BV2 cells induced by LPS with IC50 of 0.1 and 2.0 uM, respectively.
PC-20005

mPGES-1 inhibitor UK-4b

mPGES-1 inhibitor

mPGES-1 inhibitor UK-4b is a potent, hgihly selective and orally bioavailable inhibitor of human and mouse mPGES-1 enzymes with IC50 of 33 and 157 nM, respectively, effectively decreases carrageenan-stimulated PGE2 over-production.
PC-49705

mPGES-1 inhibitor PBCH

mPGES-1 inhibitor

PBCH is a selective small-molecule inhibitor of mPGES-1, which is potent and can effectively inhibit both human and rodent orthologs.
PC-49642

TAS-204

H-PGDS inhibitor

TAS-204 (TAS204) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, inhibits recombinant human H-PGDS with IC50 of 24.0 nM.
PC-49641

TAS-205 monohydrate

H-PGDS inhibitor

TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM.
PC-49640

TFC-007

H-PGDS inhibitor

TFC-007 (TFC007) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 83 nM.
PC-49639

HQL-79

H-PGDS inhibitor

HQL-79 (HQL79) is an orally selective inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS), inhibits human H-PGDS competitively against the substrate PGH2 and non-competitively against GSH with Ki of 5 and 3 uM, respectively.
PC-49638

GSK2894631A

H-PGDS inhibitor

GSK2894631A (GSK-2894631A) is a potent and specific inhibitor of hematopoietic PGD synthase (HPGDS) with IC50 of 9.9 nM.
PC-49637

H-PGDS inhibitor 1y

H-PGDS inhibitor

H-PGDS inhibitor 1y is a potent peripherally restricted hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 9.4 nM.
PC-49465

GS-248

mPGES-1 inhibitor

Vipoglanstat (GS-248, BI 1029539) is a potent, selective and orally active membrane-associated prostaglandin E synthase-1 (mPGES-1) inhibitor with IC50 of 0.4 nM in human whole-blood assay (hWBA).
PC-49237

MPO-0144

mPGES-1 inhibitor

MPO-0144 (MPO 0144) is a potent, selective mPGES-1 inhibitor (PGE2 IC50=41.77 nM, mPGES-1 IC50=1.16 nM).

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