| Cat. No. |
Product Name |
Information |
| PC-38455 |
AT-56
L-PGDS inhibitor
|
AT-56 is an orally active, selective inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with Ki of 75 uM, IC50 of 95 uM. |
| PC-36096 |
Pizuglanstat
H-PGDS inhibitor
|
TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM. |
| PC-36090 |
Crisdesalazine
mPGES-1 inhibitor
|
Crisdesalazine (AAD-2004, AAD2004) is a derivative of aspirin that inhibits microsomal PGE(2) synthase-1 (mPGES-1) activity in response to both LPS-treated BV2 cell with IC50 of 230 nM and recombinant human mPGES-1 protein with IC50 of 249 nM in vitro. |
| PC-43462 |
MF63
mPGES-1 inhibitor
|
MF63 is a potent, selective, and orally active mPGES-1 inhibitor with IC50 of 1.3 nM for human mPGES-1 enzyme, >1000-fold selectivity over other prostanoid synthases. |
| PC-43211 |
hPGDS-IN-1
H-PGDS inhibitor
|
hPGDS-IN-1 is a potent, selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor inhibitor with IC50 of 12 nM in FP or EIA assays. |
| PC-62820 |
mPGES1-IN-16
mPGES-1 inhibitor
|
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM. |
| PC-62797 |
mPGES1-IN-17d
mPGES-1 inhibitor
|
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM. |
| PC-61665 |
PF-9184
mPGES-1 inhibitor
|
PF-9184 is a potent, selective mPGES-1 (microsomal prostaglandin E synthase-1) inhibitor with IC50 of 16.5 nM. |
| PC-61406 |
LY3031207
mPGES-1 inhibitor
|
LY3031207 is a novel potent (IC50=910 ng/mL), highly selective microsomal prostaglandin E synthase 1 inhibitor (mPGES-1) for treatment of undisclosed indications. |
| PC-42585 |
HPGDS inhibitor 1
H-PGDS inhibitor
|
HPGDS inhibitor 1 is a potent, selective, oral hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with enzyme IC50 of 0.6 nM. |
| PC-45791 |
Benzydamine hydrochloride
|
Benzydamine hydrochloride is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions. |
| PC-49641 |
TAS-205 monohydrate
H-PGDS inhibitor
|
TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM. |
