| Cat. No. |
Product Name |
Information |
| PC-49640 |
TFC-007
H-PGDS inhibitor
|
TFC-007 (TFC007) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 83 nM. |
| PC-49639 |
HQL-79
H-PGDS inhibitor
|
HQL-79 (HQL79) is an orally selective inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS), inhibits human H-PGDS competitively against the substrate PGH2 and non-competitively against GSH with Ki of 5 and 3 uM, respectively. |
| PC-49638 |
GSK2894631A
H-PGDS inhibitor
|
GSK2894631A (GSK-2894631A) is a potent and specific inhibitor of hematopoietic PGD synthase (HPGDS) with IC50 of 9.9 nM. |
| PC-49637 |
H-PGDS inhibitor 1y
H-PGDS inhibitor
|
H-PGDS inhibitor 1y is a potent peripherally restricted hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 9.4 nM. |
| PC-49465 |
Vipoglanstat
mPGES-1 inhibitor
|
Vipoglanstat (GS-248, BI 1029539) is a potent, selective and orally active membrane-associated prostaglandin E synthase-1 (mPGES-1) inhibitor with IC50 of 0.4 nM in human whole-blood assay (hWBA). |
| PC-49237 |
MPO-0144
mPGES-1 inhibitor
|
MPO-0144 (MPO 0144) is a potent, selective mPGES-1 inhibitor (PGE2 IC50=41.77 nM, mPGES-1 IC50=1.16 nM). |
| PC-38689 |
LY3023703
mPGES-1 inhibitor
|
LY3023703 is a potent, highly selective microsomal prostaglandin E synthase 1 (mPGES1) inhibitor, dose-dependently inhibits PGE2 production in human whole blood ex vivo. |
| PC-38688 |
Zaloglanstat
mPGES-1 inhibitor
|
Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with IC50 of 5 nM (human mPGES-1). |
| PC-38642 |
SZ0232
mPGES-2 inhibitor
|
SZ0232 is a small molecule mPGES-2 (microsomal prostaglandin E synthase-2) inhibitor with IC50 of <1 uM, exhibits beneficial effects on modulating β-cell function and glucose metabolism both in vitro and in vivo. |
| PC-38615 |
CAY10526
mPGES-1 inhibitor
|
CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM. |
| PC-38455 |
AT-56
L-PGDS inhibitor
|
AT-56 is an orally active, selective inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with Ki of 75 uM, IC50 of 95 uM. |
| PC-36096 |
Pizuglanstat
H-PGDS inhibitor
|
TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM. |
