Goflikicept | Anti-IL-1B fusion protein

Chemical Structure : Goflikicept

CAS No.:

Goflikicept (RPH-104)

Catalog No.: PC-38883Not For Human Use, Lab Use Only.

Packing	Price	Stock
1 mg	$498	In stock
5 mg	$998	In stock
10 mg		Get quote
25 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Goflikicept (RPH-104) is a heterodimeric fusion protein containing IL-1R1 and IL-1RAcP linked to immunoglobulin heavy chains and is highly selectively binds IL-1B, affecting IL-1B signalling pathways, inhibits widespread inflammation.
Human interleukin-1 receptor accessory protein fragment (21-358, 1-338 in the current sequence) fused via peptidyl linker 339GSGGG343 to a human immunoglobulin G1 Fc fragment (344-570, C-terminal Lys clipped) variant (S>C477, T>W489, K>A532), covalent dimer with human interleukin-1 receptor type 1 fragment (21-333, 1-313 in the current sequence) fused via peptidyl linker 314GSGG318 to a human immunoglobulin G1 Fc fragment (319-545, C-terminal Lys clipped) variant (Y>C447, T>S464, L>A466, F>K503, Y>V505), glycosylated, produced in Chinese hamster ovary (CHO) cells.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility
Chemical Name/SMILES

Goflikicept (RPH-104)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.