Catalog No.: PC-62396Not For Human Use, Lab Use Only.
ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2).
ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2).
ALW-II-49-7 displays excellent overall kinase selectivity against a panel of over 350 kinases.
ALW-II-49-7 decreases DDR2 phosphorylation but has little effect on the proliferation of DDR2 mutated cancer cell lines.
