| Cat. No. |
Product Name |
Information |
| PC-43808 |
I-BET726
BET inhibitor
|
I-BET726 (GSK1324726A) is a potent and selective inhibitor of BET bromodomain with IC50 of 41 nM/31 nM/22 nM for BRD2/BRD3/BRD4 respectively. |
| PC-42230 |
TPOP146
CBP/p300 inhibitor
|
TPOP146 is a potent and selective CBP/p300 bromodomain inhibitor with Kd of 134 nM for CBP bromodomain, displays excellent selectivity over other bromodomains (>30-fold over BRD4 (1)). |
| PC-42029 |
Mivebresib
BET inhibitor
|
Mivebresib (ABBV-075) is a potent and orally available BET bromodomain inhibitor with Ki of 1.0, 12.2, 1.5, and 2.2 nM for BRD2, BRD3, BRD4 and BRDT, respectively. |
| PC-22528 |
I-BET469
BET inhibitor
|
I-BET469 is a potent, selective pan-BET bromodomain inhibitor with pIC50 of 7.9 for BRD4 BD1, >5000-fold selective over BAZ2A. |
| PC-22527 |
I-BET787
BET inhibitor
|
I-BET787 (GSK3535787) is potent, efficient pan-BET bromodomain inhibitor with pIC50 of 7.1/5.9 for BRD4 BD1/BD2, respectively. |
| PC-22485 |
Y08284
CBP/p300 inhibitor
|
Y08284 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 4.21 nM (CBP bromodomain) in HTRF assays. |
| PC-22484 |
Y08207
CBP/p300 inhibitor
|
Y08207 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 26.37 nM (CBP bromodomain) in HTRF assays. |
| PC-22483 |
Y08262
CBP/p300 inhibitor
|
Y08207 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 73.1 nM (CBP bromodomain) in HTRF assays. |
| PC-22395 |
Tafbromin
TAF1(2) inhibitor
|
Tafbromin is a selective inhibitor of TAF1 bromodomain by binding to the second bromodomain (TAF1(2)) with KD of 260 nM, inhibits Hh pathway-dependent osteoblast differentiation. |
| PC-22287 |
CDD-1302
BRDT BD2 inhibitor
|
CDD-1302 (CDD1302) is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 8 and 12 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1. |
| PC-22217 |
Rac EBET-590
BET inhibitor
|
Rac EBET-590 (EBET-590 Racemate) is a small molecule BET inhibitor. |
| PC-22216 |
EBET-590
BET inhibitor
|
EBET-590 (ER-001251206-000) is a small molecule BET inhibitor. |
