BRD-IN-17 |CAS:1914047-59-8 Probechem Biochemicals

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Chemical Structure : BRD-IN-17

BRD-IN-17

Catalog No.: PC-62278Not For Human Use, Lab Use Only.

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.
BRD-IN-17 attenuates adipocyte differentiation and dramatically decreases lipid accumulation.
BRD-IN-17 is a first in class chemical probe for Family VIII bromodomains.

Physicochemical Properties

M.Wt	362.433
Formula	C21H22N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-((6S,9R)-4-(cyclopropylamino)-6,7,8,9-tetrahydro-5H-6,9-epiminocyclohepta[d]pyrimidin-10-yl)-1-(2-hydroxyphenyl)prop-2-en-1-one

References

1. Gerstenberger BS, et al. J Med Chem. 2016 May 26;59(10):4800-11.

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BRD-IN-17

Biological Activity

Physicochemical Properties

References

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