| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38071 |
GSK778
|
2451862-42-1 |
GSK778 is a potent and selective inhibitor of bromodomain (BRD) BD1 with IC50 of 75 nM (BRD2-BD1), 41 nM (BRD3-BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. |
| PC-38064 |
ODM-207
|
1801503-93-4 |
ODM-207 (ODM207) is a highly potent, selective and orally active pan-BET inhibitor with potent and broad antiproliferative effects. |
| PC-35848 |
TP-238
|
2415263-04-4 |
TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30 nM against CECR2 and 350 nM against BPTF in an alphascreen assay, KD of 10 nM for CECR2 and 120nM for BPTF in ITC assays. |
| PC-35172 |
ABBV-744
|
2138861-99-9 |
ABBV-744 (ABBV744) is a potent, BDII-selective BET bromodomain inhibitor, ABBV-744 is a potent, selective inhibitor of the AR transcription activity. |
| PC-35097 |
ZL0454
|
2229042-77-5 |
ZL0454 is a potent, highly selective small-molecule BRD4 inhibitor with IC50 of 49 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively. |
| PC-35096 |
ZL0420
|
2229039-45-4 |
ZL0420 is a potent, highly selective BRD4 inhibitor with IC50 of 27 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively. |
| PC-63272 |
INCB057643
|
1820889-23-3 |
INCB057643 is a novel potent, selective, orally bioavailable BET inhibitor. |
