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Cat. No. Product Name Information
PC-35015

JQ1-Az

JQ1-Az is a JQ1 derivative for PROTAC synthesis.
PC-63576

GSK8814

ATAD2/2B inhibitor

GSK8814 is a potent, selective inhibitor of ATAD2/2B bromodomain binding constant pKd of 8.1 in ITC assays.
PC-63543

CBP bromodomain inhibitor 17

CBP bromodomain inhibitor

CBP-IN-17 is a potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.
PC-63487

GSK-340

BET BD2 inhibitor

GSK-340 is a potent, selective inhibitor of second bromodomains of the BET family (BD2) with pKd of 8.18, 7.49, 7.72 and 7.68 for BRD4 BD2, BRD3 BD2, BRD2 BD2 and BRD4T BD2, respectively.
PC-63272

INCB057643

BET inhibitor

INCB057643 is a novel potent, selective, orally bioavailable BET inhibitor, reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.
PC-63255

SJ830599

SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.
PC-63245

Y08060

BET inhibitor

Y08060 is a potent and selective BET inhibitor with Kd of 306 nM for BRD4 BD1, displays excellent selectivity for BET subfamily over other non-BET family with the exception of moderate inhibition of CBP/EP300.
PC-43414

I-BET151

BET inhibitor

I-BET151 (GSK1210151A) is a potent, selective BET bromodomain inhibitor with IC50 of 0.5, 0.25 and 0.79 uM for BRD2, BRD3 and BRD4 in FP assays, shows no effect on the 23 other bromodomain proteins including MLL.
PC-43341

GSK525768A

GSK525768A is an enantiomer, negative control compound of I-BET762 (GSK525762A), shows no activity against BET family proteins BRD2, BRD3 and BRD4..
PC-43340

I-BET762

BET inhibitor

I-BET762 (GSK-525762A, Molibresib) is a highly potent, selective inhibitor of BET family proteins BRD2, BRD3 and BRD4 with IC50 of 32.5-42.5 nM, does not interact with other bromodomain-containing proteins (BAZ2B, ATAD2, CREBBP and PCAF).
PC-63219

TRIM24 inhibitor X

TRIM24 inhibitor

TRIM24 inhibitor X is a potent TRIM24 bromodomain inhibitor for synthesis dTRIM24..
PC-63218

IACS-7e

TRIM24 inhibitor

IACS-7e is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement).

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