Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Bromodomain

Request The Product List ofBromodomain Bromodomain

Cat. No. Product Name Information
PC-45507

PFI-4

BRPF1 inhibitor

PFI-4 is a potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.3.
PC-42109

BI-7273

BRD9 inhibitor

BI-7273 is a potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay.
PC-45780

PF-CBP1 hydrochloride

CBP/p300 inhibitor

PF-CBP1 hydrochloride is a potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively.
PC-42090

GSK6853

BRPF1 inhibitor

GSK6853 (GSK-6853) is a potent, highly selective and cell-active BRPF1 bromodomain inhibitor with TR-FRET pIC50 of 8.1.
PC-42168

CPI-637

CBP/p300 inhibitor

CPI-637 is a potent and selective, cell-active CBP/EP300 bromodomain inhibitor with CBP BRET EC50 of 0.03 uM.
PC-43808

I-BET726

BET inhibitor

I-BET726 (GSK1324726A) is a potent and selective inhibitor of BET bromodomain with IC50 of 41 nM/31 nM/22 nM for BRD2/BRD3/BRD4 respectively.
PC-42230

TPOP146

CBP/p300 inhibitor

TPOP146 is a potent and selective CBP/p300 bromodomain inhibitor with Kd of 134 nM for CBP bromodomain, displays excellent selectivity over other bromodomains (>30-fold over BRD4 (1)).
PC-42029

Mivebresib

BET inhibitor

Mivebresib (ABBV-075) is a potent and orally available BET bromodomain inhibitor with Ki of 1.0, 12.2, 1.5, and 2.2 nM for BRD2, BRD3, BRD4 and BRDT, respectively.
PC-24390

Y08197

CBP/EP300 inhibitor

Y08197 is a selective inhibitor of CBP/EP300 bromodomain, inhibits the CBP bromodomain with IC50 of 100.67 nM, high selectivity for CBP/EP300 over other bromodomain-containing proteins.
PC-24374

ZL0516

BRD4 BD1 inhibitor

ZL0516 is a potent, selective BRD4 BD1 inhibitor with IC50 of 84 nM, shows good selectivity over other BRD family proteins including BRD4 BD2.
PC-24237

KB-0118

BET bromodomain

KB-0118 is a selective BET bromodomain inhibitor with Kd of 36.7 uM for BRD2 BD1 and 47.4 uM for BRD4 BD1, shows immunomodulatory effects in inflammatory bowel disease (IBD).
PC-23888

LC-CE-7

CECR2 inhibitor

LC-CE-7 is a potent, sepecific and allosteric covalent CECR2 inhibitor with IC50 of 462 nM and Ki of 32.5 nM, exhibits covalent binding to Cys494 and allosteric regulation of the Kac pocket.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com