| Cat. No. |
Product Name |
Information |
| PC-72184 |
GSK217
BET BD2 inhibitor
|
GSK217 (GSK-217) is a potent, highly selective BET BD2 inhibitor with pIC50 of 7.5 (BRD4 BD2), 300-fold selectivity over BRD4 BD1. |
| PC-72183 |
GSK852
BET BD2 inhibitor
|
GSK852 (GSK-852) is a highly potent, second bromodomain (BD2)-selective BET inhibitor with pIC50 7.9 (BRD4 BD2), 1260-fold selectivity over BRD4 BD1. |
| PC-72182 |
GSK046
BET BD2 inhibitor
|
GSK046 (GSK-046, iBET-BD2) is a potent, highly selective inhibitor of BET BD2 with pIC50 of 7.3 (BRD4 BD2), >1000-fold over BRD4 BD1. |
| PC-72181 |
GSK040
BET BD2 inhibitor
|
GSK040 (GSK-040) is a potent, highly selective BET BD2 inhibitor with pIC50 of 8.3 (BRD4 BD2), 5000-fold selectivity over BD1. |
| PC-72180 |
GSK549
BET BD2 inhibitor
|
GSK549 (GSK-549) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.8 (BRD4 BD2), 1150-fold selectivity over BD1. |
| PC-72179 |
GSK620
BET BD2 inhibitor
|
GSK620 (GSK-620) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.1 (BRD4 BD2), 220-fold selectivity over BD1. |
| PC-38169 |
NEO2734
CBP/p300-BET inhibitor
|
NEO2734 (NEO-2734, EP31670) is a dual inhibitor of pan-BET and CBP/p300 with Kd values of 2-31 nM. |
| PC-38148 |
Alobresib
BET inhibitor
|
GS-5829 (GS5829, Alobresib) is a novel potent, selective BET inhibitor. |
| PC-38071 |
GSK778
BRD BD1 inhibitor
|
GSK778 is a potent and selective inhibitor of bromodomain (BRD) BD1 with IC50 of 75 nM (BRD2-BD1), 41 nM (BRD3-BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. |
| PC-38064 |
ODM-207
pan-BET inhibitor
|
ODM-207 (ODM207) is a highly potent, selective and orally active pan-BET inhibitor with potent and broad antiproliferative effects. |
| PC-38040 |
Trotabresib
BET inhibitor
|
Trotabresib (CC90010) is a reversible and orally active BET bromodomain inhibitor, shows significant antiproliferative activity in glioblastoma cells and patient-derived xenograft models as monotherapy and in combination with temozolomide (TMZ). |
| PC-35931 |
Bromotriazine
BET inhibitor
|
Bromotriazine (BTZ) is a covalent probe against bromodomain containing proteins with selectively targeting
non-catalytic, highly conserved amino acid residues.. |
