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Cat. No. Product Name Information
PC-60388

UMB-136

UMB-136 (UMB136) is a novel bromodomain BRD4 inhibitor that significantly induces HIV-1 reactivation.
PC-60307

GNE-207

CBP/p300 inhibitor

GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.
PC-60306

GNE-781

CBP/p300 inhibitor

GNE-781 (GNE781) is a potent, selective, non-CNS penetrant, orally active CBP/p300 bromodomain inhibitor with IC50 of 0.94/1.2 nM in TR-FRET assays.
PC-60305

GNE-272

CBP/EP300 inhibitor

GNE-272 (GNE272) potent and selective the bromodomains of CBP/EP300 inhibitor with IC50 of 0.02 and 0.03 uM for CBP and EP300, respectively.
PC-60199

Ischemin

CBP bromodomain inhibitor

Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
PC-60104

HJB-97

BET inhibitor

HJB-97 is a potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2.
PC-70031

PF-CBP1

CBP/p300 inhibitor

PF-CBP1 is a potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively.
PC-70026

CPI-268456

BRD4 inhibitor

CPI-268456 is a small molecule ligand of bromodomain-containing protein 4 (BRD4), binds to BRD4 with IC50 of 0.5 uM in cell-free assays.
PC-60022

BAY-850

BAY-850 (BAY 850, BAY850) is a potent, isoform selective, cellularly active ATAD2 bromodomain inhibitor with binding IC50 of 166 nM in TR-FRET assay.
PC-45582

I-BRD9

BRD9 inhibitor

I-BRD9 is the first selective cellular chemical probe inhibitor for BRD9 with pIC50 of 7.3.
PC-45508

GSK-5959

BRPF1 inhibitor

GSK-5959 (GSK5959) is the first potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.1.
PC-45994

JQ-1 carboxylic acid

BET inhibitor

JQ-1 carboxylic acid is an inhibitor of bromodomain and extra terminal domain (BET) family proteins with Kd of 128, 59.5, 49.0, and 190 nM for JQ1 binding to bromodomains of BRD2, BRD3, BRD4, and BRDT, respectively, blocking their interaction with acetylated histones.

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