| Cat. No. |
Product Name |
Information |
| PC-62511 |
CPI203
BET inhibitor
|
CPI 203 (TEN 010, JQ-2, RG-6146, RO6870810) is a primary amide analog of (+)-JQ1and a BET bromodomain inhibitor that shows cytotoxicity against MCL cell lines with GI50 of 0.1-0.3 uM. |
| PC-62510 |
BET BRD4 inhibitor Compound II-25
BRD4 BD1 inhibitor
|
BET BRD4 inhibitor Compound II-25 is a potent BRD4-BD1 inhibitor with IC50 of 8 nM. |
| PC-62475 |
Olinone
BET BRD1 inhibitor
|
Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM). |
| PC-62474 |
MS417
BRD4 inhibitor
|
MS417 (GTPL-7512) is a highly specific BET bromodomain inhibitor that binds to BRD4-BD1 and BRD4 BD2 with Kd of 36.1 uM and 25.4 uM respectively. |
| PC-62389 |
GSK1379725A
BPTF inhibitor
|
GSK1379725A is the first selective small molecule inhibitor of BPTF bromodomain (bromodomain PHD finger transcription factor) with Kd of 2.8 uM in a cell-based reporter assay, shows no binding activity for Brd4. |
| PC-62317 |
GW 841819X
BET inhibitor
|
GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain that displays activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia.. |
| PC-62299 |
LP99
BRD7/BRD9 inhibitor
|
LP99 is the first potent and selective BRD7/9 bromodomain inhibitor with Kd of 99 nM for BRD9. |
| PC-62290 |
CeMMEC13
TAF1 (2) inhibitor
|
CeMMEC13 is a selective TAF1 second bromodomain (TAF1 (2)) inhibitor with IC50 of 2.1 uM. |
| PC-62289 |
CeMMEC1
TAF1 (2) inhibitor
|
CeMMEC1 is a potent, selective second bromodomain of TAF1 inhibitor with Kd of 1.8 uM. |
| PC-62288 |
CeMMEC2
BRD4 inhibitor
|
CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1. |
| PC-62287 |
BAY299
BRPF1/TAF1 inhibitor
|
BAY 299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 and the second bromodomain of TAF1 with IC50 of 6 nM and 13 nM, respectively. |
| PC-62286 |
NI-57
BRPF bromodomain inhibitor
|
NI-57 is a potent inhibitor of the bromodomain of the BRPFs and binds to BRPF1B, BRPF2 and BRPF3 and with KD of 31 nM,108 nM and 408 nM (ITC), respectively. |
