| Cat. No. |
Product Name |
Information |
| PC-62389 |
GSK1379725A
BPTF inhibitor
|
GSK1379725A is the first selective small molecule inhibitor of BPTF bromodomain (bromodomain PHD finger transcription factor) with Kd of 2.8 uM in a cell-based reporter assay, shows no binding activity for Brd4. |
| PC-62317 |
GW 841819X
BET inhibitor
|
GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain that displays activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia.. |
| PC-62299 |
LP99
BRD7/BRD9 inhibitor
|
LP99 is the first potent and selective BRD7/9 bromodomain inhibitor with Kd of 99 nM for BRD9. |
| PC-62290 |
CeMMEC13
TAF1 (2) inhibitor
|
CeMMEC13 is a selective TAF1 second bromodomain (TAF1 (2)) inhibitor with IC50 of 2.1 uM. |
| PC-62289 |
CeMMEC1
TAF1 (2) inhibitor
|
CeMMEC1 is a potent, selective second bromodomain of TAF1 inhibitor with Kd of 1.8 uM. |
| PC-62288 |
CeMMEC2
BRD4 inhibitor
|
CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1. |
| PC-62287 |
BAY299
BRPF1/TAF1 inhibitor
|
BAY 299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 and the second bromodomain of TAF1 with IC50 of 6 nM and 13 nM, respectively. |
| PC-62286 |
NI-57
BRPF bromodomain inhibitor
|
NI-57 is a potent inhibitor of the bromodomain of the BRPFs and binds to BRPF1B, BRPF2 and BRPF3 and with KD of 31 nM,108 nM and 408 nM (ITC), respectively. |
| PC-62285 |
BRPF1B TRIM24-IN-34
BRPF1B/TRIM24 inhibitor
|
BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively. |
| PC-62284 |
FT-1101
BET inhibitor
|
FT-1101 is a potent pan-BET bromodomain inhibitor that displays equipotent inhibition for BRD2, BRD3, BRD4, and BRDT with Kd < 20 nM. |
| PC-62283 |
BAY1238097
BET inhibitor
|
BAY 1238097 is a novel BET bromodomain inhibitor with IC50 of 50 nM, inhibits the interaction between BRD4, BRD3 or BRD2 and H4 with IC50 values of 63 nM, 609 nM and 2430 nM in the NanoBRET assay. |
| PC-62282 |
CPI-0610
BET inhibitor
|
Pelabresib (CPI-0610) is a potent, selective, and cell-active BET bromodomain inhibitor with IC50 of 39 nM for BRD4-BD1 in TR-FRET assay. |
