| Cat. No. |
Product Name |
Information |
| PC-60930 |
Dual BET-Kinase inhibitor 3
BET inhibitor
|
Dual BET-Kinase inhibitor 3 is a potent, dual BET bromodomain-kinase inhibitor with IC50 of 34, 1.1 and 1.1 nM for BRD4 BD1, JAK2 and FLT-3, respectively. |
| PC-60857 |
CPI644
CREBBP/EP300
|
CPI644 (CPI-644) is a potent, selective, cell-active CREBBP/EP300 bromodomain inhibitor with IC50 of 0.18 uM for CREBBP. |
| PC-60856 |
CPI703
CBP/EP300 inhibitor
|
CPI-703 (CPI703) potent, selective, cell-active CBP/EP300 bromodomain inhibitor with IC50 of 0.47 uM for CBP. |
| PC-70222 |
GS-626510
|
GS-626510 (GS-6510, GS 6510, GS 626510) is a novel BET family bromodomains inhibitor with Kd of 0.5-2.8 nM for BRD2/3/4, and BRDT. |
| PC-60389 |
UMB-32
BRD4 inhibitor
|
UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM. |
| PC-60388 |
UMB-136
|
UMB-136 (UMB136) is a novel bromodomain BRD4 inhibitor that significantly induces HIV-1 reactivation. |
| PC-60307 |
GNE-207
CBP/p300 inhibitor
|
GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM. |
| PC-60306 |
GNE-781
CBP/p300 inhibitor
|
GNE-781 (GNE781) is a potent, selective, non-CNS penetrant, orally active CBP/p300 bromodomain inhibitor with IC50 of 0.94/1.2 nM in TR-FRET assays. |
| PC-60305 |
GNE-272
CBP/EP300 inhibitor
|
GNE-272 (GNE272) potent and selective the bromodomains of CBP/EP300 inhibitor with IC50 of 0.02 and 0.03 uM for CBP and EP300, respectively. |
| PC-60199 |
Ischemin
CBP bromodomain inhibitor
|
Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
| PC-60198 |
Ischemin sodium
CBP bromodomain inhibitor
|
Ischemin sodium is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
| PC-60104 |
HJB97
BET inhibitor
|
HJB-97 (HJB97) is a potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2. |
