| Cat. No. |
Product Name |
Information |
| PC-61007 |
NI-42
BRPF1 inhibitor
|
BRPF1 inhibitor NI-42 (NI-42) is a potent, selective and orally active BRPF1 bromodomain inhibitor with IC50 of 7.9 nM, with excellent selectivity over nonclass IV BRDs. |
| PC-60935 |
RX-37
BET inhibitor
|
RX-37 (RX37) is a potent and specific BET bromodomain inhibitor with Ki of 3.2-24.7 nM for BD1 and BD2 domains of BRD2, BRD3, and BRD4. |
| PC-60932 |
BETi-211
|
BETi-211 is a novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM. |
| PC-60930 |
Dual BET-Kinase inhibitor 3
BET inhibitor
|
Dual BET-Kinase inhibitor 3 is a potent, dual BET bromodomain-kinase inhibitor with IC50 of 34, 1.1 and 1.1 nM for BRD4 BD1, JAK2 and FLT-3, respectively. |
| PC-60857 |
CPI644
CREBBP/EP300
|
CPI644 (CPI-644) is a potent, selective, cell-active CREBBP/EP300 bromodomain inhibitor with IC50 of 0.18 uM for CREBBP. |
| PC-60856 |
CPI703
CBP/EP300 inhibitor
|
CPI-703 (CPI703) potent, selective, cell-active CBP/EP300 bromodomain inhibitor with IC50 of 0.47 uM for CBP. |
| PC-70222 |
GS-626510
|
GS-626510 (GS-6510, GS 6510, GS 626510) is a novel BET family bromodomains inhibitor with Kd of 0.5-2.8 nM for BRD2/3/4, and BRDT. |
| PC-60389 |
UMB-32
BRD4 inhibitor
|
UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM. |
| PC-60388 |
UMB-136
|
UMB-136 (UMB136) is a novel bromodomain BRD4 inhibitor that significantly induces HIV-1 reactivation. |
| PC-60307 |
GNE-207
CBP/p300 inhibitor
|
GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM. |
| PC-60306 |
GNE-781
CBP/p300 inhibitor
|
GNE-781 (GNE781) is a potent, selective, non-CNS penetrant, orally active CBP/p300 bromodomain inhibitor with IC50 of 0.94/1.2 nM in TR-FRET assays. |
| PC-60305 |
GNE-272
CBP/EP300 inhibitor
|
GNE-272 (GNE272) potent and selective the bromodomains of CBP/EP300 inhibitor with IC50 of 0.02 and 0.03 uM for CBP and EP300, respectively. |
