BETi-211 |CAS:1995867-02-1 Probechem Biochemicals

Chemical Structure : BETi-211

BETi-211 (BETi 211;BETi211)

Catalog No.: PC-60932Not For Human Use, Lab Use Only.

BETi-211 is a novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM.

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Biological Activity

BETi-211 is a novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM.
BETi-211 exhibits >10-100 times more potent than RX-37, JQ-1, OTX-015 or IBET-762.

Physicochemical Properties

M.Wt	487.564
Formula	C26H29N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)-7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-2-(methoxymethyl)-9H-pyrimido[4,5-b]indol-4-amine

References

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BETi-211 (BETi 211;BETi211)

Biological Activity

Physicochemical Properties

References

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